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What is pseudohypoparathyroidism ?

Pseudohypoparathyroidism  is a condition with increased  secretion of parathormone (PTH) is there but due to end organ resistance, there is no response to PTH hormone resulting in clinical features of hypoparathyroidism. This is a hereditary disorder with distinctive skeletal and developmental defects. These patients have elevated levels of serum PTH.
The common features are :
  • Short height with stocky built.
  • Round face with short neck.
  • Mental retardation.
  • Epileptic convulsions.
  • Short 4th and 5th metacarpals and metatarsals.
  • Basal ganglia calcification.