A site for medical students - Practical,Theory,Osce Notes

Thyroid and cardiac abnormalities

Thyroid examination is done for evidence of hypo  and hyperthyroidism  which can lead to heart disease.
Signs of thyroid dysfunction
  • Tachycardla/bradycardia, tremor, warmth
  • Exophthalmos and eye signs
  • Goitre

Blood supply of internal capsule

Blood supply of internal capsule comes from 3 main arteries they are
Lateral striate branches of middle cerebral artery.
Medial striate branches of anterior cerebral artery.
Anterior choroidal branches of internal carotid artery.

Lateral striate branches of middle cerebral artery supply
  1. Anterior limb.
  2. Genu.
  3. Posterior limb.
  4. Basal ganglia.
Medial striate branches of anterior cerebral artery supply
  1. Anterior limb.
  2. Genu.
  3. Basal ganglia.
Anterior choroidal branches of internal carotid supply
  1. Posterior limb.
  2. Retrolenticular part.
Anterior limb is supplied by the following arteries
  1. Ant cerebral artery through medial striate branch.
  2. Middle cerebral artery through lateralstriate and lenticulostriate branches.
Genu is supplied by
  1. Anterior cerebral artery through medial striate branch.
  2. Middle cerebral artery through lateral striate and lenticulostriate branch.
  3. Branches of internal carotid artery.
Posterior limb is supplied by
  1. Middle cerebral artery through lateral striate and lenticulostriate branch. It is called Charcot’s artery of cerebral haemorrhage.
  2. Anterior choroidal artery, direct branch of internal carotid artery As it is long and slender it has tendency to get thrombosis.

Mechanism of continuous murmur

1.High pressure system communicating with low pressure system
  • RSOV to RV, RA ,Pulmonary artery.
  • Coronary artery fistula to cardiac chamber.
  • PDA.
  • Aorto pulmonary septal defect.
  • Pulmonary AVF.
  • Systemic AVF.
  • Anomalous left coronary artery from pulmonary artery.
2.Narrowing of vessel
  • Coarctation of aorta.
  • Peripheral pulmonary artery stenosis.
  • Carotid stenosis.
3.Increased blood flow through vessels
  • Venous hum - Devil’s murmur - root of neck.
  • Venous hum (Cruveilhier – Baumgarten murmur) - umbilicus - in portal hypertension.
  • Intercostal arteries - Coarctation of aorta.
  • Bronchopulmonary anastomoses.
  • Pulmonary atresia and TOF.
  • Internal mammary artery - Mammary Souffle in pregnancy.

Vascular theories of Migraine

It is the most common Migraine is the most common disabling primary headache globally.

12 percent of migraine are Episodic and 1 - 2 percentage is Chronic.Migraine Attacks are typically present with unilateral throbbing headache and it is associated with following  symptoms 

  1. Nausea
  2. Multisensory Hypersensitivity
  3. Marked fatigue.

The diverse symptomatology highlights the complexity of migraine as a whole nervous system disorder involving somatosensory, autonomic, endocrine, and arousal networks

Vascular Theory of Aura in Migrane

In Migraine  there is Hereditary Susceptibility of Brain. There is Abnormal Intracranial and extra-cranial  vascular reactivity to triggers. Aura is followed by Vasoconstriction, ischemia and focal neurological symptoms. Headache is due to Vasodilation and leads to pulsatile headache

What are the Pitfalls in Vascular theory

MRI perfusion study has showed that there is focal hyperemia precedes oligemia during Migraine aura. Perfusion abnormalities need not always match with symptoms of migraine. Oligemia may spread at 3mm/min beyond vascular territory. Headache can occur as that of migraine aura. Vascular theory cannot explain the premonitory phase. There wont be any Diffusion restriction in  MRI doesn’t show  

Normal Second heart sound (Identify the abnormalities of S2)

The most difficult thing in auscultation is to identify the abnormalities of S2.

Physiology of Second heartsound
Two components for 2nd heart sound are- aortic and pulmonary

Aortic component it is the 1st component and loud one heard in all areas.

Pulmonary component - 2nd component and soft, heard only over pulmonary area.

Normal second heart sound
It is a high pitched sound with normal split - 2 components are separately heard during inspiration and as single component during expiration over the pulmonary area.
Distance between the 2 components during inspiration is 0.04 sec, during expiration is 0.02 sec. Human ear can appreciate, when the distance between the 2 components is 0.03 or more. Normal second heart sound is expressed as - normal in intensity and normal split with respiration.

Things to look for in S2:
A2 heard over aortic area and pulmonary area and the apex.
P2 heard over pulmonary area and 2-4 LICS only and not at the apex.
P2 heard over the apex only in pulmonary artery hypertension and in young.
Best site for S2 in COPD - epigastrium.

NINDS (National Institute of Neurological Disorders and Stroke ) criteria for possible PSP

NINDS criteria for possible PSP

  • Gradually progressive disorder with onset aged 40 years or older.
  • Either vertical supra nuclear palsy or both slowing of vertical saccades and prominent postural instability with falls in the first year of onset.
  • No evidence of other diseases that can explain the clinical features.

Criteria for probable PSP

Vertical supranuclear palsy with prominent postural instability, falls in the first year of onset, and other features of possible PSP, as follows:

  • Symmetric proximal greater than distal akinesia or rigidity.
  • Abnormal neck posture, especially retrocollis.
  • Poor or absent response of parkinsonism to levodopa therapy.
  • Early dysphagia and dysarthria.
  • Early cognitive impairment with at least 2 of the following: apathy, abstract thought impairment, decreased verbal fluency, imitation behavior, or frontal release signs.

Criteria for definite PSP are as follows:

  • History of probable or possible PSP.
  • Histopathologic evidence that is typical of the disease.

Measurements of abdomen

  1. Abdominal girth should be measured at the level of umbilicus
  2. Periodic measurement is done to assess prognosis in ascites, paralytic ileus.
  3. Measure the distance between lower end of xiphisternum to umbilicus and from umbilicus to symphysis pubis. Normally umbilicus is in mid position, it is displaced down in ascites, upper abdominal mass, displaced upwards  in ovarian or pelvic tumors
  4. Spinoumbilical measurement - It is the  distance between umbilicus and anterior superior iliac spines. Normally they are equidistant. Shift of umbilicus to one side will occur in case of tumors that originating from the other side of the abdomen.